Metrics details. Peer Review reports. Chronic obstructive pulmonary disease COPD is currently the third leading cause of death in the world [ 1 ]. The most common symptoms include dyspnea, cough and sputum production, with the symptoms worsening during exacerbations. For the treatment of stable COPD patients, inhaled bronchodilators play a central role in reducing symptoms and exacerbations.
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Review report Corman-Drosten et al. Eurosurveillance – CORMAN-DROSTEN REVIEW REPORT
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The characters of Fruits Basket were created by Natsuki Takaya in the manga written and illustrated by her. The series tells the story of Tohru Honda, an orphan girl who, after meeting Yuki, Kyo, and Shigure Soma, learns that thirteen members of the Soma family are possessed by the animals of the Chinese zodiac and cursed to turn into their animal forms when they embrace someone of the opposite sex or their bodies come under a great deal of stress. As the series progresses, Tohru meets the rest of the zodiac and the family's mysterious head, Akito Soma, and eventually resolves to break the curse that burdens them.
This distinction is normally lost outside Japan, as both visual novels and adventure games are commonly referred to as "visual novels" by international fans. Visual novels are rarely produced for video game consoles , but the more popular games have occasionally been ported to systems such as the Sega Saturn , Dreamcast , PlayStation Portable , or Xbox The more famous visual novels are also often adapted into light novels , manga or anime.